Alumni

Peter Vosler, Ph.D.

Graduated: August, 2009
Mentor: Dr. Jun Chen
Thesis: Critical role of eukaryotic translation initiation factor 4G degradation in mediating ischemia-induced neuronal death
Current Position: Otolaryngology Resident University of Pittsburgh Medical Center
Email:
Prior Degree: BS Quinnipiac University (2000)

Publications:

Vosler, P.S., Graham, S.H., Wechsler, L. and Chen, J. Mitochondrial targets for stroke: Focusing basic science research toward development of clinically translatable therapeutics. (Submitted).

Vosler, P.S. and Chen, J. Calpsin-modulation of programmed cell death pathways in cerebral ischemia. In G.Y. Yang and K. Jin (Eds.), Research Progress in Experimental Stroke. Oak Park, IL, Benthan Science Publications, In press.

Gao, Y., Cao, G., Xing, Q., Iwai, M., Vosler, P., Shen, H., Zhang W, Signore, A. and Chen J. Limiting hypoxic-ischemic brain injury by inhibition of the apoptotic protease activating factor-1 signaling pathway. Neurological Research (in press).

Vosler, P.S., Chen J. Potential molecular targets for translational stroke research. Stroke. Dec 8, 2008. [Epub ahead of print]

Stetler, R.A., Cao, G., Gao, Y., Zhang, F., Wang, S., Weng, Z., Vosler, P., Zhang, L., Signore, A., Graham, S.H. and Chen, J. Hsp27 protects against ischemic brain injury via attenuation of a novel stress-response cascade upstream of mitochondrial cell death signaling. J Neurosci. Dec 3;28(49): 13038-55, 2008.

Wang, S., Xing, Z., Vosler, P.S., Yin, H., Li, W., Zhang, F., Signore, A.P., Stetler, R.A., Gao, Y. and Chen, J. Cellular NAD releplenishment confers marked neuroprotection against ischemic cell death: role of enhanced DNA repair. Stroke. Sep;39(9): 2587-95, 2008.

Vosler, P.S., Brennan, C.S. and Chen, J. Calpain-mediated signaling mechanisms in neuronal injury and neurodegeneration. Mol Neurobiol. Aug;38(1): 78-100, 2008.

Vosler, P.S., Logue, E.S., Repine, M.J. and Callaway, C.W. Delayed hypothermia preferentially increases expression of brain-derived neurotrophic factor exon III in rat hippocampus after asphyxial cardiac arrest. Brain Res Mol Brain Res. Apr 27;135(1-2): 21-9, 2005.